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Reduced expression of the polymeric immunoglobulin receptor in pancreatic and periampullary adenocarcinoma signifies tumour progression and poor prognosis

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J Pharmacol Exp Ther 265:12391244 McCarty MF, DiNicolantonio JJ (2020) Nutraceuticals have potential for boosting the type 1 interferon response to RNA viruses including influenza and coronavirus

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30 In adolescents with obesity, semaglutide 2.4 mg once weekly led to weight loss similar to that observed in adults (a 16.1% mean reduction in BMI from baseline vs 0.6% with placebo at 68 weeks), along with improvements in cardiometabolic risk factors such as waist circumference, glycated haemoglobin (HbA 1c ), LDL-cholesterol, triglyceride and alanine transaminase levels