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This enzyme relies entirely on a steady supply of GSH to catalyze the reduction of hydrogen peroxide (H2O2) and lipid peroxides into water and harmless alcohols

Possibly both, in the article's framing

An Auristatin nanoconjugate targeting CXCR4+ leukemic cells blocks acute myeloid leukemia dissemination

Rotating injection sites actually supports consistent effectiveness by preventing tissue adaptation at any single location

JAMA Netw Open 7(7):e2421305e2421305 Emerenziani S, Pier Luca Guarino M, Trillo Asensio LM, Altomare A, Ribolsi M, Balestrieri P, Cicala M (2019) Role of overweight and obesity in gastrointestinal disease