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In the last decade, the clinical burden of NAFLD has been associated to liver-related morbidity and mortality and also to the extra-hepatic manifestations involving other organs and regulatory pathways

None of this is an argument against medication where it's needed

[11] In other words, people engaging in this experiment are doing so without the guidance of any researchit is essentially uncharted territory

Evidence shows that high dietary salt intake and fasting can induce obesity by promoting hyperphagia and endogenous fructose production, which in turn trigger LR

For surgical planning , current guidance from the American Society of Anesthesiologists and partner societies (2024) indicates that most patients can continue GLP-1 receptor agonists perioperatively with individualized risk assessment