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Its discovery opened a new chapter in sleep science, establishing that the brain produces discrete peptide signals capable of modulating sleep architecture a concept that has since expanded into a broader field of sleep-regulatory neuropeptide research

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Conventionally, the main goal of radiotherapy has been to kill cancer cells, notwithstanding the local immunosuppression through various pathways such as vascular disruption and hypoxia, which might result in diminished recruitment of certain immune effector cells, exhaustion of effector T cells, and stimulation of regulatory T cells (321, 332334)

Trends in peptide drug discovery