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Additionally, lysosome-associated membrane protein 3 (LAMP3) is elevated within the salivary glands of specific individuals suffering from SS, and the resulting lysosomal dysfunction serves as a crucial factor in the evolution of the disease [280]

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Yamanaka, A., Hirai, T., Ohtake, Y

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However, along with its potent anti-hyperglycemia effects, insulin also carries a high risk of hypoglycemia, often leads to weight gain, and some types of insulin have been linked to increased rates of several cancers (Karlstad 2013