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One study (from 1999) mentions the issue described above, but it is not a credible source for the following reasons: The study wasn't performed on normal human proteins or healthy, intact skin (instead, a blend of animal and human proteins, and the pH relationship issue developed only when a fatty acid byproduct was added to the mix)

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5-Amino 1MQ and NNMT Inhibition

2 Pharmaceutical Applications Dermatological Medications: Used in prescription formulations for treating chronic wounds, burns, and ulcerations due to its tissue regenerative properties

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