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Protects Against Oxidative Stress Acts as a first line of defense against damage caused by reactive oxygen species

10.1016/j.brainres.2010.05.090 Brain Res

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Tao CC, Hsu WL, Ma YL, Cheng SJ, Lee EH

Moreover, preclinical RF models exhibit significant limitations: UUO and I/R models induce acute severe fibrosis that does not mimic the gradual progression of human CKD-related RF and lacks comorbidities (e.g., diabetes and hypertension) that are common in clinical settings