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The most frequent symptoms include nausea, vomiting, diarrhoea, abdominal pain, and constipation

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Excess adipose tissue produces estrogen through aromatization of androgens, disrupting the hypothalamic-pituitary-gonadal axis

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However, he explained that high blood sugar levels can contribute to heart attacks and strokes and lead to vascular dementia or multi-infarct dementia. Research has shown that calorie restriction may be associated with longevity