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Male SpragueDawley (SD) rats (78 weeks old, 200250 g) were obtained from Beijing Vital River Laboratory Animal Technology Co., Ltd

For human DRG lysates, 30 g of denatured protein was loaded for western blotting and probed with primary antibodies (IFN from Thermo Fisher Scientific and -actin from Abcam) in a similar protocol as described above using antibodies listed in Supplementary Table 9

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