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This mechanism significantly reduces the risk of hypoglycemia when used alone, though this risk increases when combined with insulin or sulfonylureas

In the context of atherosclerosis, IF can reduce LDL-C and attenuate systemic inflammation, such as the suppression of IL-6 and TNF, which may exert anti-atherogenic effects (Moro et al., 2021)

10.1001/jama.2021.3224 [DOI] [PMC free article] [PubMed] [Google Scholar] 34.Rubino DM, Greenway FL, Khalid U, O'Neil PM, Rosenstock J, Srrig R, et al

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