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proposed that the N-terminal region (residues 2446 of CLIC1) may form a transmembrane helix in the chloride ion channel 17

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Traditionally, two types of therapeutic agents have been used to treat T2D: insulin or its analogues, such as insulin lispro and insulin aspart, as well as oral medications such as glipizide, glimepiride, metformin, acarbose, pioglitazone, and saxagliptin [3]

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As a result, some people may eat less protein than recommended, leading to muscle mass loss