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Signs of deficiency include: Fatigue and low energy Memory issues and brain fog Numbness or tingling in the hands and feet Mood swings or depression Pale skin and shortness of breath Supplementing Safely: Dosage and Absorption Tips While B12 is generally safe as its water-soluble (meaning excess is excreted), certain considerations can help you get the most out of your supplement: Sublingual Supplements : These are absorbed directly into the bloodstream, bypassing the digestive system, making them ideal for those with absorption issues

But these studies were tiny and had no placebo group

If you maintain a hectic lifestyle that results in poor nutrition or high-stress levels, you may benefit from a boost to sustain your energy

Once-weekly cagrilintide for weight management in people with overweight and obesity

Food-induced lowering of blood-ethanol profiles and increased rate of elimination immediately after a meal