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This work provided direct imaging evidence that complemented prior studies on bulk copper release [225, 232]
In this study, we used non-targeted metabolomics to identify changes in the aqueous humor of glaucoma patients
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All samples and standards must be in Sample Diluent before starting the assay
Translational studies using exosomes showed a relationship between the epigenetic modulation of glutamatergic function and a brain metabolic dysfunction known as insulin resistance (IR) as showed by an increase and sex-specific phosphorylation in the expression of IRS1, a key marker of the insulin signaling cascade, in discrete exosomes enriched for the neural cell adhesion molecule L1 (L1CAM), a protein highly expressed in the brain [52, 70,71,72]
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