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doi: 10.1111/j.1523-1755.2004.00773.x
Although mitochondrial respiration was noted as unchanged in resting and stimulated CD4+ and CD8+ T cells, CD8+ T cells were found to have a reduction in proton leak, ATP synthesis, and mitochondrial membrane potential (254)
Therefore, aside from the DNA damage resulting from the promotion of OS due to tobacco, smoking initiates pathways influenced by ROS, connecting to RAS/MAPK, NF-B, and AP-1, contributing to inflammation, programmed cell death, proliferation, and cell specialization
(D) Colocalization analysis of microscopy data using the JACoP plugin of ImageJ
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