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& Broer, S

The mitochondrial membrane permeabilization results in the release of the proapoptotic factors from the mitochondrial intermembrane space, cytochrome c [194], AIF [195], and endonuclease G [196], to the cytosol

TM6SF2 E167K, transmembrane 6 superfamily member two amino acid 167 E to K mutation

For larger time zone shifts, gradual adjustment over two to three weeks works well

We also generated the following lines by combining strains obtained from the CGC: IU613 [ fem-3(e1996)/nT1 [qIs51] (IV;V) ], IU619 [ fog-3(q470)/hT2 (bli-4(e937) let-?(q782) qIs48) (I;III)] , IU653 [ mog-3(q74)/hT2 (bli-4(e937) let-?(q782) qIs48) (I;III) ], IU658 [ mog-3(q74)/hT2 (bli-4(e937) let-?(q782) qIs48) (I;III)