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The small number of patients who received a CTLA-4 inhibitor, a PD-1/PD-L1 inhibitor, or a combination of immune checkpoint inhibitors limits the comparison between our findings and the findings in other studies related to these checkpoint inhibitor classes

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Thus, arginine functions as a microbial energy source, governs the expression of bacterial virulence genes, and actively modulates the hosts immune response to the gut microbiota (Choi et al., 2012)