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In skin, this can result in: Photodamage (premature aging) Hyperpigmentation Fine lines Lower collagen content Dull-looking skin As one of the master antioxidants throughout the body, glutathione wields the reparative powers to help suspend the process of accelerated oxidative stress and restore the appearance and function of healthy skin

[17] The ratio of reduced glutathione to oxidized glutathione within cells is a measure of cellular oxidative stress [18] [11] where increased GSSG-to-GSH ratio is indicative of greater oxidative stress

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As a consequence, the use of NSAIDs was, and is still, discouraged while the alternative adoption of paracetamol is still preferred