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Is there a compounding factor that the sicker people with diabetes or obesity were more likely to have been prescribed semaglutide? he says

Some variability in the study findings is likely attributable to inconsistent definitions of red meat

GLP-1 receptor deficiency in the diabetic nephropathy-resistant C57BL/6-Akita mouse contributes to the development of diabetic nephropathy, and liraglutide treatment suppressed the progression of nephropathy of the KK/Ta-Akita mouse, which shows high susceptibility to diabetic nephropathy [14], suggesting that GLP-1 action might play an important role in prevention of diabetic nephropathy

An interesting question this survey raises is whether the results reflect the medication alone or everything that surrounds it

In the COMBINE 2 trial in individuals with T2D inadequately controlled with GLP-1RA, with or without additional oral glucose-lowering medications, IcoSema as compared to semaglutide 1.0 mg provided superiority in HbA 1c reduction from baseline to week 52 and greater improvement in fasting plasma glucose with comparable rate of combined clinically significant or severe hypoglycemia, while the weight change was in favor of semaglutide 1.0 mg [14]