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In simple terms, semaglutide targets one hormone that makes you feel full and controls blood sugar, while tirzepatide targets two hormones that are shown to have greater improvements in metabolic health, including better insulin sensitivity and fat burning

This is particularly significant in neurodegenerative disorders such as Parkinsons disease, where the depletion of GSH intensifies the degeneration of dopaminergic neurons in the substantia nigra (SN) [15,16,27]

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