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The agreement calls for co-commercialization in the US and Europe, while Roche secures exclusive rights in the rest of the world and will manage commercial manufacturing and supply through its extensive global network

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NAC may be useful when: Cysteine availability may be limiting The goal is to support internal glutathione synthesis Direct glutathione is poorly tolerated A clinician has identified a relevant medical or nutritional reason NAC does not guarantee that glutathione production will increase adequately

doi: 10.1007/978-3-319-71779-1_3 33

CT, P = 0.066)