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228 , e13334 (2020)

FOXO4-DRI a D-retro-inverso peptide made from protease-resistant D-amino acids competitively displaces endogenous FOXO4 from p53, freeing p53 to activate its apoptotic program selectively in senescent cells (Baar et al., 2017)

Under the Federal Food, Drug, and Cosmetic Act (FDCA), selling unapproved peptides for human consumption can violate statutes prohibiting the introduction of misbranded or adulterated drugs into interstate commerce (21 U.S.C

They are not intended for human use and have not been evaluated by the FDA for diagnosing, treating, curing, or preventing any disease