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J Womens Health (Larchmt) 25 , 865874, (2016)

Currently, available treatments only alleviate symptoms without halting or delaying disease progression

Contrasting effects of lixisenatide and liraglutide on postprandial glycemic control, gastric emptying, and safety parameters in patients with type 2 diabetes on optimized insulin glargine with or without metformin: A randomized, open-label trial

Biomedicines 11(7):1964 Shokri M et al (2021) Adjuvant use of melatonin for relieving symptoms of painful diabetic neuropathy: results of a randomized, double-blinded, controlled trial

In particular, in both studies, liraglutide 1.8 mg/day induced a significant increase in SHBG and a decrease in free testosterone