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Downtime: None resume normal activities immediately

Capecitabine therapy has been shown to shift microbial taxa and enhance pathways for menaquinone (vitamin K) biosynthesis, which correlated with reduced chemotherapy-related toxicities, particularly peripheral sensory neuropathy (61)

As to the pain "going in" it may be that the needle caught a nerve or vein plus the fact that you were probably a little tense and nervous