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Sperber H, Mathieu J, Wang Y, et al

Dysregulated gut homeostasis observed prior to the accumulation of the brain amyloid- in Tg2576 mice

The SLC7A1 encoded transporter is the primary transporter for the cellular uptake of arginine whereas the antiporter composed of the SLC7A6 encoded protein is the major arginine efflux transporter for transport of arginine out of cells

While renal dysfunction progresses, the most important indicators of oxidative stress are plasma F2-isoprostanes, 8-oxo-7,8-dihydro-2-deoxyguanosine, malondialdehyde (MDA), carbamylated proteins, advanced oxidation protein products, asymmetric dimethylarginine, and oxidized lipoprotein particles (138, 141, 142)