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Novo Nordisks Response to JAMA Study and Allegations In an emailed statement, Wegovy manufacturer Novo Nordisk countered that there were several limitations of the JAMA study design, which was not a randomized controlled trial, as reported by Reuters

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It regulates appetite and food intake, leading to significant weight loss when combined with lifestyle modifications

It is important to reduce the intake of sugary beverages as well as carbonated beverages, which can sometimes exacerbate the gastrointestinal side effects of the medication"