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As a core enzyme in epigenetic regulation, Enhancer of zeste homolog 2 (EZH2) serves as a pivotal node linking epigenetic regulation, tumorigenesis, immune control, and ferroptosis, providing novel therapeutic insights for anti-tumor immunity

Skin Lightening Reactions: In rare cases, uneven or excessive skin lightening may occur, especially if not administered under medical supervision

The specific dosage and frequency are determined by the prescribing provider based on the patients clinical condition, therapeutic goals, and response to treatment

However, creatine status cannot be inferred from SAM alone and should be interpreted in the wider clinical and metabolic context

Publication Bias We used Egger's test to estimate the possibility of publication bias