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The inhibition of serine and glycine bidirectional conversion by sertraline prior irradiation reduces the pool of nucleotides, as we previously observed, and concurrent and post-treatment with sertraline might hinder the synthesis of the antioxidant GSH and NADPH production, which exposes cancer cells to the accumulation of endogenous ROS and radiation-induced ROS causing severe oxidative stress [70]

Yang ZL, Zhang ZS (2018) Engineering strategies for enhanced production of protein and bio-products in Pichia pastoris : a review

Sunscreen use is essential during the day, as tretinoin increases sensitivity to sunlight

This stimulates the release of nitric oxide, leading to vasodilation and a transient drop in blood pressure