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But the gut is also home to trillions of microbes that influence metabolism

After pushback from the compounding pharmacies, the agency agreed to reevaluate its decision, but in December 2024, it announced it would be sticking with its original call

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Heres what weve found: Effectiveness Rather than packing its capsules with as many probiotic strains as possible ( la competitor Seed), Pendulums catalog sticks to a small roster of five species with substantial research supporting their effects on gut health, metabolism, diabetes management, and weight control: , found in clinical trials to help people reduce BMI and improve diabetic biomarkers12 Akkermansia muciniphila , an effective species against common gastrointestinal (GI) pathogens16 Clostridium butyricum , shown to inhibit fat storage and reduce serum cholesterol24 Anaerobutyricum hallii , capable of supporting other beneficial bacterial species in the gut while inhibiting harmful ones9 Clostridium beijerinckii , an alleviator of irritable bowel symptoms26 Bifidobacterium infantis Pendulum includes all five species in its Metabolic Daily and Glucose Control supplements, and exclusively Akkermansia in its product of the same name