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Injection Site Reactions Mild redness, itching, or tenderness at the injection site Usually resolves within 2448 hours Rotating sites (abdomen, thigh, upper arm) and allowing the pen to reach room temperature before injecting reduces reactions Serious Side Effects When to Call Your Doctor Immediately These are uncommon but require immediate medical attention

NMDA receptor activation, a key mechanism in central sensitization, is modulated by magnesium

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Because it interacts with more than one metabolic receptor, some individuals experience stronger appetite regulation or improved metabolic markers