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Clinical signs of B12 deficiency include nausea, vomiting, loss of appetite, poor absorption of food (malabsorption syndrome), constipation, gas, weight loss, fatigue, lethargy, abdominal pain, and diarrhea

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In hydrogen sulfide SIBO, the overgrowth is dominated by bacteria that produce hydrogen sulfide gas (H2S)

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If only pathway 2 is activated, the existing pathway is triggered without re-initiation

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