Adjunct treatment with fenofibrate (145-160 mg/d), a PPAR agonist, increases serum bile acid glucuronides to reduce bile acid toxicity during refractory cholestasis in PBC and PSC vs
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However, many women with endometriosis are normal weight or underweight, and in these cases, GLP-1-mediated estrogen changes may be minimal or even counterproductive
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Risks include weight gain, hypoglycemia, pancreatitis, cirrhosis, heart disease, cancer, mental health issues, and an increased likelihood of accidents