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The mechanism of action involves several complementary pathways: Enhanced insulin secretion : GLP-1 agonists stimulate glucose-dependent insulin release from pancreatic beta cells, meaning insulin is only released when blood glucose levels are elevated, thereby reducing the risk of hypoglycaemia

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Because it lacks the albumin-binding linker of the DAC form, its plasma half-life more closely resembles native GHRH, making it a distinct reference compound for comparative GHRH-receptor pharmacokinetic studies and pulsatile somatotroph-stimulation models

Strijbis, K., Vaz, F