Drawing lessons from other countries approaches to covering GLP-1 drugs, LDI Senior Fellow Ezekiel Emanuel and colleagues give four key guidelines that should inform future policies to ensure fair and effective access to these critical medications across the U.S
For instance, Hulst et al (2021)178 recommended continuation of all GLP-1RAs therapies throughout the perioperative period
Further analysis revealed that morronisides therapeutic effects are reliant on the spinal microglial expression of IL-10 and subsequent -endorphin production [74]
The goal is to understand why inflammatory signaling is elevated and whether modifiable drivers are present: visceral fat, periodontal disease, poor sleep, alcohol, insulin resistance, autoimmune activity, environmental exposure, chronic infection, or unresolved cardiometabolic risk
ELIZABETH MCDONALD: The weight loss alone just didn't account for the magnitude of the observed effect