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It is most commonly used to prevent: Thiamine deficiency in dogs and cats Thiamine deficiency-induced polioencephalomalacia (PEM) of sheep and cattle In dogs and cats, thiamine deficiency occurs after an incomplete and unbalanced diet because thiamine is a normal dietary requirement in mammals

K., Baluka, F

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J Allergy Clin Immunol (2020) 146(2):33743 e6

As further consideration of translation of this therapeutic to the clinic, cochlear synaptopathy is implicated as a potential contributor to human tinnitus, although the published evidence is emerging and, so far, is largely indirect 11,60