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Rapid weight loss itself can contribute to musculoskeletal discomfort as the body adapts to changes in biomechanics, muscle mass, and joint loading patterns

The injections are well-tolerated, with most patients describing them as less uncomfortable than standard insulin injections

Additionally, TFR1, acyl-CoA synthetase family member 2 (ACSF2), and heme oxygenase-1 (HO-1) expression were significantly upregulated, leading to increased ferroptosis in the optic nerves of locally demyelinated MS mice