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Source: ADA Conference 2023 Despite these positive data points, it would be prudent to dive deeper and consider the potential impacts across multiple areas: MedTech companies that make devices related to bariatric surgery for weight loss should anticipate that physicians will aim to exhaust non-surgical options

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FIGURE 2 Patch-clamp studies testing the effects of bath-applied GLP-1 demonstrated that activating the receptor in hippocampal neurons evoked acute membrane potential changes, proving that GLP-1 receptors exist in the hippocampus and can induce acute neuronal changes ( 140 reduced the frequency of miniature inhibitory and excitatory postsynaptic currents (mEPSCs) (mIPSCs) in rat CA1 pyramidal neurons

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Recent advancements in sampling strategies, bio-analytics, and dosing decision support offer opportunities to address these limitations