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At the same dose, a 74 kg participant had about 1.4 times the exposure of a 110 kg reference, while a 143 kg participant had about 0.8 times. Weight alone does not set the dose, but it helps explain why the trial mean transfers poorly to bodies outside the studied range

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DISCLAIMER: This compound has not been evaluated by the FDA

Its targeted mechanism of action makes it a valuable compound for investigating how NNMT inhibition influences metabolic health, mitochondrial function, and longevity-associated biological processes

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