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Defective PCFT also leads to impaired folate transport into the brain (see Disease Treatment)

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The data were further normalized to the median value of total lipid signals

Notably, hippocampal synaptic dysfunction in SOD1(G93A) mice was rescued by pharmacological blockade of A 2A receptors, suggesting a pathogenic role for adenosinergic signaling in early disease stages [434]

A study by Leem et al 28 demonstrated that the measured data of facial characteristics using the Janus-III system showed highly correlated patterns with those evaluated by a dermatologist