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Researchers often notice effects only when comparing before-and-after states over weeks

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(1997) ArticleTitleThe influence of a novel pentadecapeptide BPC 157 on N G -nitro-L-arginine methylester and L-arginine effect on stomach mucosal integrity and blood pressure Eur J Pharmacol 332 2333 Occurrence Handle9298922 Occurrence Handle10.1016/S0014-2999(97)01033-9 V Bedekovic S Mise T Anic M Staresinic M Gjurasin M Kopljar et al

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Medications including metformin, proton pump inhibitors, and H2-receptor antagonists may reduce absorption of B12, potentially prolonging the time to clinical improvement