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In particular, Arsenic is a semi-metal with a complex ambivalent biochemical behavior: it is both a recognized human carcinogen and a curative anti-leukaemia drug and in both phenomena, its binding with cellular bio-thiols such as glutathione and with protein thiol groups is essential

Chromosome 1p13.3 holds the 10 exon-containing GSTM1 gene, while chromosome 22q11.23 is where the 6 exon-containing GSTT1 gene is located

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