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Results The p53 TAD2 region plays a crucial role in the interaction with FOXO4 FHD Interactions between FOXO4 and p53 in the nucleus have been reported to promote cellular senescence 34

PMID: 88 RichardsJ

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These models have provided a service in the development of therapies for Graves disease, including immune-modulatory treatments targeting autoimmune components of the disease, and thus laid the groundwork for therapeutic advances in human patients (Kahaly 2020)