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While pyridoxine (vitamin B6) is typically considered helpful in reducing vomiting and nausea, the American Academy of Family Physicians (AAFP) mentions that cyanocobalamin (vitamin B12) also significantly reduced vomiting episodes in pregnant women compared with placebo, indicating its role in nausea and vomiting management

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If your side effects are severe, however, or if they dont subside after and adjustment period even if theyre not severe, your provider may need to adjust your dosage or make other changes to your treatment

Fatigue is usually temporary and often related to reduced calorie intake, hydration levels, or blood sugar changes as your body adjusts

Rotate injection sites systematically (abdomen, thigh, or upper arm), and avoid injecting into areas with existing irritation, scarring, or skin changes