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Proc Jpn Acad Ser B Phys Biol Sci 85(1):1236 Carbone DL, Doorn JA, Kiebler Z, Petersen DR (2005) Cysteine modification by lipid peroxidation products inhibits protein disulfide isomerase

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Both medications target more than one metabolic receptor, but retatrutide activates an additional pathway that may enhance fullness and metabolic signaling