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The Fertiliser I use a plant analogy to reframe this for my patients

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Int J Mol Sci 22(19):10713 Yamakawa H, Kato TS, Noh JY, Yuasa S, Kawamura A, Fukuda K et al (2021) Thyroid hormone plays an important role in cardiac function: from bench to bedside

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Second, safety and ethical concerns persist, particularly for injectable systems such as PEGylated uricase, where immunogenicity and long-term tissue accumulation necessitate rigorous riskbenefit analyses