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Challenges in Research While extensive research supports the benefits of both antioxidants individually as well as their combined effectthere remains ongoing debate about optimal dosing regimens particularly concerning supplementation, which highlights challenges faced by researchers due largely due variability of human physiological responses alongside limitations inherent experimental designs, thus necessitating continued rigorous study under controlled conditions before making definitive conclusions

Theoretical considerations regarding cell proliferation effects should be considered

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Animal studies show foetal harm risks like growth restriction, and the drugs pass into breast milk, potentially affecting infants

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