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The hormones examined were ghrelin, peptide tyrosine tyrosine (PYY), glucagon-like peptide -1 (GLP-1), and cholecystokinin (CCK), in their total and/or active form

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The findings suggest that weight loss can enhance the effectiveness of circulating estradiol (a potent form of oestrogen), as lower body fat reduces estrone production, which can counteract the beneficial effects of estradiol

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