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DCD grafts were given an initial bolus of 10 mg tPA, followed by a 40 mg infusion over 90 minutes

EPR spectroscopy allowed recognizing the generation of reaction products of DMPO that derive from its reaction with superoxide (in its turn, recognized from its disappearance from the reaction mixture after incubation with superoxide dismutase)

Positive improvements in the GSSG/GSH ratio were observed immediately after exhaustive exercise following the intervention, compared to pre-intervention levels

Methods: We performed whole-transcriptome sequencing (n=5) based on the liver tissues of responders (R) and non-responders (NR) from ten PBC/AIH OS patients

Serum levels of ADP, pro-C3, and MACK-3 score (a score for active and fibrotic NASH calculated from HOMA, AST and CK-18) were measured at baseline (BL) and end of treatment (EOT)