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The L-371,257 powder was dissolved in 10% dimethyl sulfoxide (DMSO) in phosphate buffered saline (PBS)

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Doctors usually suggest lifestyle changes instead

The piece below covers Novi's program structure, eligibility context, and the April 2026 regulatory environment from an awareness-stage perspective - complementary background for anyone working through the enrollment decision

Guidelines from bodies such as the Endocrine Society and AACE (American Association of Clinical Endocrinology) recommend considering GLP-1 RAs (or other anti-obesity medications) in patients with BMI 30, or 27 with weight-related comorbidities, when lifestyle measures alone are insufficient