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[DOI] [PMC free article] [PubMed] [Google Scholar] 47.Haeusler R.A., Hartil K., Vaitheesvaran B., Arrieta-Cruz I., Knight C.M., Cook J.R., Kammoun H.L., Febbraio M.A., Gutierrez-Juarez R., Kurland I.J., et al

Interestingly, the aryl hydrocarbon receptor (AhR) of the tryptophan-kynurenine pathway serves as a critically important mediator between tryptophan metabolism, immune reactions, and tissue homeostasis (4143), and several kynurenine metabolites have been associated with fatigue (44, 45)