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Neurotrophic factors such as brain-derived neurotrophic factor (BDNF) and insulin-like growth factor-1 (IGF-1) are fundamental for neuronal survival, plasticity, and synaptic integrity 44,45

113 H 2 S is then released upon the reaction of activated 3-MST with a sulphane sulphur acceptor such as thioredoxin, cysteine, homocysteine, glutathione, or even n -acetylcysteine, thus generating the corresponding per-sulphides

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Whilst clinical trials have not established a direct link between Mounjaro and loss of libido, some patients report changes in sexual function during treatment